KU70

Ku70 - Wikipedia

Ku70 is a protein that, in humans, is encoded by the XRCC6 gene. Contents. 1 Function; 2 Aging; 3 Clinical; 4 Nomenclature; 5 Interactions; 6 References ...

ku70

XRCC6 - X-ray repair cross-complementing protein 6 - Homo ...

5'-dRP lyase Ku70. 70 kDa subunit of Ku antigen. ATP-dependent DNA helicase 2 subunit 1. ATP-dependent DNA helicase II 70 kDa subunit. CTC box-binding ...

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Ku70 - an overview | ScienceDirect Topics

Ku70 is a component of a heterodimeric Ku protein that is required for non- homologous end-joining DNA repair, VDJ recombination, telomerase maintenance ...

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Ku70 suppresses the apoptotic translocation of Bax to mitochondria.

Nat Cell Biol. 2003 Apr;5(4):320-9. Ku70 suppresses the apoptotic translocation of Bax to mitochondria. Sawada M(1), Sun W, Hayes P, Leskov K, Boothman DA  ...

ku70

Anti-Ku70 antibody (ab83501) | Abcam

Rabbit polyclonal Ku70 antibody. Validated in WB, IP, IHC, ICC/IF and tested in Human. Cited in 4 publication(s). Independently reviewed in 4 review(s).

ku70

HDAC6 deacetylates Ku70 and regulates Ku70-Bax binding in ...

Ku70 was first characterized as a nuclear factor that binds DNA double-strand breaks in nonhomolog end-joining DNA repair. However, recent studies have ...

ku70

Ku70 (IPR006165) - InterPro entry - InterPro

Homologues of the eukaryotic DNA-end-binding protein Ku were identified in several bacterial and one archaeal genome using iterative database searches; ...

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Ku Regulates Signaling to DNA Damage Response Pathways ...

The Ku heterodimer (Ku70/Ku80) is a main component of the nonhomologous end-joining (NHEJ) pathway that repairs DNA double-strand breaks (DSBs).

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Regulation of the proapoptotic factor Bax by Ku70-dependent ...

24 Mar 2008 ... The DNA end-joining protein Ku70 is one of several proteins that inhibit apoptosis by sequestering the proapoptotic factor Bax from the ...

ku70

2547 - Gene ResultXRCC6 X-ray repair cross complementing 6 ...

X-ray repair cross-complementing protein 6, 5'-dRP lyase Ku70, 5'-deoxyribose-5 -phosphate lyase Ku70, 70 kDa subunit of Ku antigen, ATP-dependent DNA ...

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Ku70 (V540) Antibody - CST

Polyclonal Antibody for studying Ku70 in the Cell Cycle / Checkpoint research area.

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The Ku70/80 ring in Non-Homologous End-Joining: easy to slip on ...

Front Biosci (Landmark Ed). 2019 Jan 1;21:514-27. The Ku70/80 ring in Non- Homologous End-Joining: easy to slip on, hard to remove. Kragelund BB(1) ...

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KU70 Antibody 10723-1-AP | Proteintech

HeLa cells were subjected to SDS PAGE followed by western blot with 10723-1- AP(KU70 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 ...

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Expression of Ku70 and Ku80 Mediated by NF-κB and ...

29 Nov 2002 ... Ku70 and Ku80 mRNA expression was assessed by RT-PCR analysis, followed by Southern hybridization, and quantitated using the β-actin ...

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pEGFP-C1-FLAG-Ku70 - Addgene

Plasmid pEGFP-C1-FLAG-Ku70 from Dr. Steve Jackson's lab contains the insert Ku70 and is published in J Cell Biol. 2013 Jul 29. This plasmid is available ...

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XRCC6 Gene - GeneCards | XRCC6 Protein | XRCC6 Antibody

Heterodimer composed of XRCC5/Ku80 and XRCC6/Ku70. The dimer associates in a DNA-dependent manner with PRKDC to form the DNA- dependent protein ...

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Ku70 Antibody (A-9) | SCBT - Santa Cruz Biotechnology

Ku70 Antibody (A-9) is a monoclonal Ku70 antibody that detects human Ku70 by WB, IP, IF, IHC(P), FCM and ELISA. Cited in 52 publications.

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Ku70 Antibody | Bethyl Laboratories, Inc.

Unconjugated Whole IgG Rabbit anti-Ku70 Antibody, Affinity Purified suitable for WB, IP applications. Visit Bethyl.com for all your antibody needs.

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Ku70 Functions in Addition to Nonhomologous End Joining in ...

28 Feb 2013 ... In the present study, to further delineate the function of NHEJ, we analyzed mice deficient for another key NHEJ factor, Ku70, to discover the ...

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Ku70 Antibody (MA5-13110)

Invitrogen Anti-Ku70 Monoclonal (N3H10), Catalog # MA5-13110. Tested in Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ...

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EGCG induces lung cancer A549 cell apoptosis by regulating Ku70 ...

21 Jan 2019 ... Ku70 was first characterized as part of the Ku70/Ku80 heterodimer that is essential as a DNA binding component of the non-homologous end ...

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EAF2 regulates DNA repair through Ku70/Ku80 in the prostate ...

10 Oct 2019 ... Further analysis showed that EAF2 and EAF1 are required for the recruitment and retention of Ku70/Ku80 to DNA damage sites and play a ...

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Anti-Ku70 antibody (GTX101820) | GeneTex

Rabbit Polyclonal Ku70 antibody. Validated in WB, ICC/IF, IHC-P, IP, PLA. Tested in Human. Cited in 9 reference(s).

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Anti-Ku70 Antibody Products | Biocompare.com

524 products ... Listed below are anti-Ku70 antibodies from multiple suppliers. Ku70 is a reported alias name for the human gene XRCC6, or 'X-ray repair cross ...

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KU70 Rabbit pAb-Polyclonal Antibodies - ABclonal

Rabbit KU70 Rabbit pAb (A7330), validaed in WB,, IHC,, IF,, IP and tested in Human,, Mouse,, Rat. 100% Guaranteed. ABclonal provides free trial antibodies for ...

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Phosphorylation of Ku70 subunit by cell cycle kinases modulates the ...

8 Jul 2019 ... Abstract. The Ku protein, a heterodimer of Ku70 and Ku80, binds to chromosomal replication origins maximally at G1-phase and plays an ...

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AT1G16970(KU70)

24 Jul 2019 ... Ku80 and ku70 form the heterodimer complex Ku, required for proper maintenance of the telomeric C strand. Ku regulates the extension of the ...

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YKU70 | SGD

25 May 2007 ... Summary: Subunit of the Ku70:Ku80 complex; binds RNA and damaged DNA; involved in telomere maintenance, chromatin silencing, and ...

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Abstract 1745: Ku70 suppresses alternative end-joining in G1 ...

1 Jul 2019 ... Abstract 1745: Ku70 suppresses alternative end-joining in G1-arrested progenitor B cells. Richard L. Frock, Vipul Kumar, Zhouyi Liang, Jeff ...

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Ku70 Corrupts DNA Repair in the Absence of the Fanconi Anemia ...

9 Jul 2010 ... Fig. 1. Suppression of cross-linker sensitivity and chromosome breakage in ∆ Ku70∆FANCC DT40 cells. (A to C) Cisplatin sensitivity of NHEJ ...

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Ku70 Is Required for Late B Cell Development and Immunoglobulin ...

15 Jun 1998 ... Immunoglobulin (Ig) heavy chain (HC) class switch recombination (CSR) is a late B cell process that involves intrachromosomal DNA ...

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Human RECQ1 Interacts with Ku70/80 and Modulates DNA End ...

1 May 2013 ... We show that RECQ1 interacts directly with the Ku70/80 subunit of the DNA-PK complex, and depletion of RECQ1 results in reduced ...

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Castration Therapy Results in Decreased Ku70 Levels in Prostate ...

15 Mar 2013 ... After castration, two to four similar biopsies were obtained, and the levels of Ku70 and γ-H2AX foci were determined by immunofluorescence in ...

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Molecular Mechanism for the Downregularion of KU70 in Apoptotic ...

16 Nov 2004 ... Abstract. Bax is a pro-apoptotic protein that plays a key role in apoptosis. Ku70 has been known as a DNA repair protein in the nucleus.

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Cutting Edge: Ku70 Is a Novel Cytosolic DNA Sensor That Induces ...

15 Apr 2011 ... A pull-down assay using cytosolic proteins identified that Ku70 and Ku80 are the DNA-binding proteins. The knockdown studies and the ...

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Deacetylation of Ku70 regulates ionizing-radiation induced DNA ...

2 Apr 2014 ... Ku70 in hetero-trimeric complex with Ku80 and DNA-PKcs represents a crucial component of the non-homologous end joining (NHEJ) DNA ...

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Ku70 - Wikipedia, la enciclopedia libre

Ku70 es una proteína codificada en humanos por el gen XRCC6.​ Ku70, junto con Ku80, conforman un heterodímero denominado proteína Ku, que se une a ...

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Effect of Ku70 expression on radiosensitivity in renal carcinoma 786 ...

26 May 2014 ... Up-regulation of Ku70 expression of 786-O cells could inhibit cell apoptosis and reduce susceptibility to radiation. On the contrary, 786-O cells ...

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Acetylation of nuclear localization signal controls importin-mediated ...

29 Aug 2019 ... Ku70 participates in various intra-and extra-nucleic processes. For multifunctional control, machinery that precisely regulates the intracellular ...

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DeubiKuitylation: A novel DUB enzymatic activity for the DNA repair ...

The Ku70 protein was shown to be involved in multiple cellular pathways including DNA repair, telomere maintenance, V(D)J recombination and Bax mediated ...

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